SB-0107 (Trapidil, AR-12008)

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Chemical Structure : SB-0107

CAS No.: 15421-84-8

Catalog No.: PC-27342Not For Human Use, Lab Use Only.

SB-0107 (Trapidil, AR-12008) is a positive allosteric modulator of a positive allosteric modulator of protein kinase A type II (PKA-II), is also a vasodilator and antiplatelet agent that antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production.

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$128	In stock
50 mg	$198	In stock
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB-0107 (Trapidil, AR-12008) is a positive allosteric modulator of a positive allosteric modulator of protein kinase A type II (PKA-II), is also a vasodilator and antiplatelet agent that antagonizes platelet-derived growth factor (PDGF), inhibits phosphodiesterase, thromboxane A2 synthesis and pro-inflammatory cytokine production.

Physicochemical Properties

M.Wt	205.27
Formula	C10H15N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N-Diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

References

1. Bordbar A, et al. Sci Transl Med. 2026 Jul 15;18(858):eaec7409.

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