SB-0110 | PKA-II PAM | Probechem Biochemicals

Chemical Structure : SB-0110

SB-0110 (SB0110)

Catalog No.: PC-27341Not For Human Use, Lab Use Only.

SB-0110 is a positive allosteric modulator of protein kinase A type II (PKA-II), reduces both parkinsonism and l-dopa-induced dyskinesia in animal models of Parkinson's disease.

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Biological Activity

SB-0110 is a positive allosteric modulator of protein kinase A type II (PKA-II), reduces both parkinsonism and l-dopa-induced dyskinesia in animal models of Parkinson's disease.

Physicochemical Properties

M.Wt	209.29
Formula	C10H11D4N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N-bis(ethyl-1,1-d2)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

References

1. Bordbar A, et al. Sci Transl Med. 2026 Jul 15;18(858):eaec7409.

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SB-0110 (SB0110)

Biological Activity

Physicochemical Properties

References

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