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SB-379278A

Chemical Structure : SB-379278A

CAS No.: 146366-04-3

SB-379278A (SB379278A;SB 379278A)

Catalog No.: PC-60135Not For Human Use, Lab Use Only.

SB-379278A is potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB-379278A is potent and selective HDAC8 inhibitor with IC50 of 0.5 uM.

Physicochemical Properties

M.Wt 177.225
Formula C8H7N3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Pyridin-4-yl-1,3-dihydroimidazole-2-thione

References

1. Hu E, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):720-8.

2. Chakrabarti A, et al. Future Med Chem. 2016 Sep;8(13):1609-34.

3. Heimburg T, et al. J Med Chem. 2017 Dec 15. doi: 10.1021/acs.jmedchem.7b01447.

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