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SB-657510

Chemical Structure : SB-657510

CAS No.: 474960-44-6

SB-657510 (SB657510)

Catalog No.: PC-28275Not For Human Use, Lab Use Only.

SB-657510 (SB657510) is a potent, selective nonpeptidic urotensin-II receptor (U-II, UTR) antagonist, binds to monkey UT receptor with KD of 2.6 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB-657510 (SB657510) is a potent, selective nonpeptidic urotensin-II receptor (U-II, UTR) antagonist, binds to monkey UT receptor with KD of 2.6 nM.

Physicochemical Properties

M.Wt 505.81
Formula C19H22BrClN2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-Bromo-N-(4-chloro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)-4,5-dimethoxybenzenesulfonamide

References

1. Douglas SA, et al. Br J Pharmacol. 2005 Jul;145(5):620-35.

2. Behm DJ, et al. Br J Pharmacol. 2008 Oct;155(3):374-86.

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