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Chemical Structure : SB-699393
Catalog No.: PC-63027Not For Human Use, Lab Use Only.
SB-699393 (SB699393) is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM.
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SB-699393 (SB699393) is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM.
SB-699393 possesses enhanced CNS penetration (BB ratio=0.8:1) compared with SB-590885.
| M.Wt | 403.482 | |
| Formula | C24H25N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Takle AK, et al. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4373-6.
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