SB-699393 |CAS:1348166-93-7 Probechem Biochemicals

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Chemical Structure : SB-699393

SB-699393 (SB699393)

Catalog No.: PC-63027Not For Human Use, Lab Use Only.

SB-699393 is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB-699393 is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM; possesses enhanced CNS penetration (BB ratio=0.8:1) compared with SB-590885.

Physicochemical Properties

M.Wt	403.482
Formula	C24H25N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-((5-(5-(morpholinomethyl)-2-(pyridin-4-yl)furan-3-yl)-2,3-dihydro-1H-inden-1-ylidene)amino)methanol

References

1. Takle AK, et al. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4373-6.

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SB-699393 (SB699393)

Biological Activity

Physicochemical Properties

References

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