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SB-U015

Chemical Structure : SB-U015

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SB-U015 (SB-U 015)

Catalog No.: PC-21382Not For Human Use, Lab Use Only.

SB-U015 is a MitoQ derivative and tumor necrosis factor receptor-associated protein 1 (TRAP1) inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SB-U015 is a MitoQ derivative and tumor necrosis factor receptor-associated protein 1 (TRAP1) inhibitor.
    SB-U015 exhibits about 2-fold higher cancer cell-specific cytotoxicity than MitoQ.
    SB-U015 alleviates retinal pathologies via proteolytic HIF1α degradation, which is mediated by opening of the mitochondrial permeability transition pore and activation of calcium-dependent protease calpain-1.

    Physicochemical Properties

    M.Wt 648.84
    Formula C38H49O5PS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (10-(4,5-dimethoxy-2-methylphenyl)decyl)triphenylphosphonium methanesulfonate

    References

    1. So-Yeon Kim, et al. Adv Sci (Weinh). 2023 Nov 20:e2302776.

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