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Chemical Structure : SB-U015
Catalog No.: PC-21382Not For Human Use, Lab Use Only.
SB-U015 is a MitoQ derivative and tumor necrosis factor receptor-associated protein 1 (TRAP1) inhibitor.
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SB-U015 is a MitoQ derivative and tumor necrosis factor receptor-associated protein 1 (TRAP1) inhibitor.
SB-U015 exhibits about 2-fold higher cancer cell-specific cytotoxicity than MitoQ.
SB-U015 alleviates retinal pathologies via proteolytic HIF1α degradation, which is mediated by opening of the mitochondrial permeability transition pore and activation of calcium-dependent protease calpain-1.
| M.Wt | 648.84 | |
| Formula | C38H49O5PS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. So-Yeon Kim, et al. Adv Sci (Weinh). 2023 Nov 20:e2302776.
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