Chemical Structure : SB 202190
CAS No.: 152121-30-7
Catalog No.: PC-42512Not For Human Use, Lab Use Only.
SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively.
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SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively.
SB 202190 stimulates the activity of CPP32-like caspases, potentiates apoptosis induced by Fas(APO-1) ligation or UV irradiation.
M.Wt | 331.343 | |
Formula | C20H14FN3O | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 40 mg/mL |
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Chemical Name/SMILES |
Phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]- |
1. Davies SP, et al. Biochem J. 2000 Oct 1;351(Pt 1):95-105.
2. Nemoto S, et al. J Biol Chem. 1998 Jun 26;273(26):16415-20.
3. Manthey CL, et al. J Leukoc Biol. 1998 Sep;64(3):409-17.
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