Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Ras-Raf-MAPK-ERK Pathway-p38 MAPK-SB 202190
SB 202190

Chemical Structure : SB 202190

CAS No.: 152121-30-7

SB 202190 (SB202190, SB-202190)

Catalog No.: PC-42512Not For Human Use, Lab Use Only.

SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively.

Packing Price Stock Quantity
5 mg (Free Sample) $28 In stock
25 mg $98 In stock
50 mg $148 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively.
SB 202190 stimulates the activity of CPP32-like caspases, potentiates apoptosis induced by Fas(APO-1) ligation or UV irradiation.

Physicochemical Properties

M.Wt 331.343
Formula C20H14FN3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 40 mg/mL

Chemical Name/SMILES

Phenol, 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-

References

1. Davies SP, et al. Biochem J. 2000 Oct 1;351(Pt 1):95-105.

2. Nemoto S, et al. J Biol Chem. 1998 Jun 26;273(26):16415-20.

3. Manthey CL, et al. J Leukoc Biol. 1998 Sep;64(3):409-17.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: