SBC110736 | PCSK9 inhibitor | Probechem Biochemicals

Chemical Structure : SBC110736

CAS No.: 1629166-02-4

SBC110736 (SBC-110736)

Catalog No.: PC-20907Not For Human Use, Lab Use Only.

SBC110736 is a small molecule inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), reduces the release of dsDNA from UVB-induced keratinocytes.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$158	In stock
25 mg	$278	In stock
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Biological Activity

SBC110736 is a small molecule inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), reduces the release of dsDNA from UVB-induced keratinocytes.
SBC110736 inhibits UVB-induced activation of the cGAS-STING pathway in macrophages.

Physicochemical Properties

M.Wt	413.52
Formula	C26H27N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(2-phenyl-4-(p-tolyl)piperazine-1-carbonyl)phenyl)acetamide

References

1. Chao Luan, et al. J Biol Chem. 2023 Jul;299(7):104895.

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SBC110736 (SBC-110736)

Biological Activity

Physicochemical Properties

References

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