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SBI-0090799

Chemical Structure : SBI-0090799

CAS No.: 464907-40-2

SBI-0090799 (SBI 0090799)

Catalog No.: PC-38240Not For Human Use, Lab Use Only.

SBI-0090799 (SBI 0090799) is a selective and potent inhibitor of Zika virus (ZIKV) replication, inhibits replication of multiple ZIKV strains and in different cell systems.

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    Biological Activity

    SBI-0090799 (SBI 0090799) is a selective and potent inhibitor of Zika virus (ZIKV) replication, inhibits replication of multiple ZIKV strains and in different cell systems.
    SBI-0090799 did not affect viral entry or RNA translation but suppressed RNA replication by preventing the formation of the membranous replication compartment.
    SBI-0090799 is functioning through inhibition of NS4A-mediated formation of ZIKV replication compartments in the endoplasmic reticulum (ER).

    Physicochemical Properties

    M.Wt 309.409
    Formula C20H23NO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (2E)-N-benzyl-3-(4-butoxyphenyl)prop-2-enamide

    References

    1. Riva L, et al. J Virol. 2021 Oct 27;95(22):e0099621.

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