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SBI-0090799

Chemical Structure : SBI-0090799

CAS No.: 464907-40-2

SBI-0090799 (SBI 0090799)

Catalog No.: PC-38240Not For Human Use, Lab Use Only.

SBI-0090799 (SBI 0090799) is a selective and potent inhibitor of Zika virus (ZIKV) replication, inhibits replication of multiple ZIKV strains and in different cell systems.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SBI-0090799 (SBI 0090799) is a selective and potent inhibitor of Zika virus (ZIKV) replication, inhibits replication of multiple ZIKV strains and in different cell systems.
SBI-0090799 did not affect viral entry or RNA translation but suppressed RNA replication by preventing the formation of the membranous replication compartment.
SBI-0090799 is functioning through inhibition of NS4A-mediated formation of ZIKV replication compartments in the endoplasmic reticulum (ER).

Physicochemical Properties

M.Wt 309.409
Formula C20H23NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2E)-N-benzyl-3-(4-butoxyphenyl)prop-2-enamide

References

1. Riva L, et al. J Virol. 2021 Oct 27;95(22):e0099621.

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