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SC-51089

Chemical Structure : SC-51089

CAS No.: 146033-03-6

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SC-51089 (SC 51089, SC51089)

Catalog No.: PC-26606Not For Human Use, Lab Use Only.

SC-51089 (SC51089) is a selective antagonist of prostaglandin E2 EP1 receptor, with Ki values of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively, exhibits neuroprotective activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SC-51089 (SC51089) is a selective antagonist of prostaglandin E2 EP1 receptor, with Ki values of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively, exhibits neuroprotective activity.

Physicochemical Properties

M.Wt 422.87
Formula C22H19ClN4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-Chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide

References

1. Lee K, et al. Xenobiotica. 1994 Jan;24(1):25-36.

2. Anglada-Huguet M, et, al. Mol Neurobiol. 2014 Apr;49(2):784-95.

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