SC-75416 | COX-2 inhibitor | Probechem Biochemicals

Chemical Structure : SC-75416

Catalog No.: PC-25009Not For Human Use, Lab Use Only.

SC-75416 (Tigemocoxib) is a potent, selective cyclooxygenase-2 (COX-2) inhibitor with IC50 of 0.25 uM, 200-fold selective over COX-1.

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Biological Activity

SC-75416 (Tigemocoxib) is a potent, selective cyclooxygenase-2 (COX-2) inhibitor with IC50 of 0.25 uM, 200-fold selective over COX-1.

M.Wt	334.72
Formula	C15H14ClF3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-1-Benzopyran-3-carboxylic acid, 6-chloro-7-(1,1-dimethylethyl)-2-(trifluoromethyl)-, (2S)-

1. Wang JL, et al. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7159-63.

2. Gierse J, et al. Eur J Pharmacol. 2008 Jun 24;588(1):93-8.