Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : SCF-I2
CAS No.: 99827-46-0
Catalog No.: PC-61192Not For Human Use, Lab Use Only.
SCF-I2 is an allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $288 | In stock | |
| 25 mg | $478 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SCF-I2 is an allosteric, sepecific inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase with IC50 of 6.2 uM in FP assays.
SCF-I2 does not affect the activity of the closely related E3 enzyme SCFMet30.
SCF-I2 inhibits binding and/or ubiquitination of both full length Sic1 and Far1 with IC50 of 60 uM.
| M.Wt | 342.35 | |
| Formula | 22H14O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-(2-carboxynaphth-1yl)-2-naphthoic acid |
|
1. Orlicky S, et al. Nat Biotechnol. 2010 Jul;28(7):733-7.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
