Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Proton-sensing GPCRs-SD2758
SD2758

Chemical Structure : SD2758

CAS No.: 2750527-08-1

Add to Favorites

SD2758 (SD-2758)

Catalog No.: PC-23386Not For Human Use, Lab Use Only.

SD2758 is a small molecule inhibitor of GPR65, inhibits pH-dependent cAMP induction with sub-micromolar IC50 values at pH 7.5 and between 1 and 10 µM at pH 7.

Packing Price Stock Quantity
2 mg $218 In stock
5 mg $358 In stock
10 mg $548 In stock
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SD2758 is a small molecule inhibitor of GPR65, inhibits pH-dependent cAMP induction with sub-micromolar IC50 values at pH 7.5 and between 1 and 10 µM at pH 7.
SD2758 augments the cytotoxic activity of antigen-specific human T-cells.
GPR65 inhibition is associated with a higher production of pro-inflammatory cytokines.

Physicochemical Properties

M.Wt 379.24
Formula C18H16Cl2N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

methyl 2-((3,4-dichlorophenyl)carbamoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxylate

References

1. Shamin Li, et al. Front Immunol. 2024 Oct 17:15:1483258.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: