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SDZ 220-581

Chemical Structure : SDZ 220-581

CAS No.: 174575-17-8

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SDZ 220-581 (SDZ 220 581)

Catalog No.: PC-43361Not For Human Use, Lab Use Only.

SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice.

Physicochemical Properties

M.Wt 369.7366
Formula C16H17ClNO5P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 8.57 mg/mL
Chemical Name/SMILES

[1,1'-Biphenyl]-3-propanoic acid, α-amino-2'-chloro-5-(phosphonomethyl)-, (αS)-

References

1. Urwyler S, et al. Neuropharmacology. 1996 Jun;35(6):655-69.

2. McAllister KH. Eur J Pharmacol. 1996 Oct 31;314(3):307-11.

3. Bakshi VP, et al. J Pharmacol Exp Ther. 1999 Feb;288(2):643-52.

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