SDZ 220-581 ammonium salt |CAS:179411-94-0 Probechem Biochemicals

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Chemical Structure : SDZ 220-581 ammonium salt

CAS No.: 179411-94-0

SDZ 220-581 ammonium salt

Catalog No.: PC-43362Not For Human Use, Lab Use Only.

SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice. .

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SDZ 220-581 is a potent, competitive NMDA receptor antagonist with pKi of 7.7, fully protects against maximal electroshock seizures (MES) at oral doses of 10 mg/kg in rats and in mice.

Physicochemical Properties

M.Wt	386.7672
Formula	C16H20ClN2O5P
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: < 3.9 mg/mL
Chemical Name/SMILES	[1,1'-Biphenyl]-3-propanoic acid, α-amino-2'-chloro-5-(phosphonomethyl)-, monoammonium salt, (S)- (9CI)

References

1. Urwyler S, et al. Neuropharmacology. 1996 Jun;35(6):655-69.

2. McAllister KH. Eur J Pharmacol. 1996 Oct 31;314(3):307-11.

3. Bakshi VP, et al. J Pharmacol Exp Ther. 1999 Feb;288(2):643-52.

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SDZ 220-581 ammonium salt

Biological Activity

Physicochemical Properties

References

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