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Chemical Structure : SEMBL
CAS No.: 1443448-82-5
Catalog No.: PC-62804Not For Human Use, Lab Use Only.
SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $178 | In stock | |
| 25 mg | $378 | In stock | |
| 100 mg | Get quote |
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SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65.
SEMBL inhibits LPS-induced NF-κB activation, iNOS expression, and inflammatory cytokine secretions.
SEMBL also inhibits NF-κB and cellular invasion in ovarian carcinoma ES-2 cells.
SEMBL enhances stability in aqueous solution compared with (-)-DHMEQ.
| M.Wt | 233.223 | |
| Formula | C12H11NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-2-hydroxy-N-(4-methylene-5-oxotetrahydrofuran-3-yl)benzamide |
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1. Sidthipong K, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):562-566.
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