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Chemical Structure : SF-1-066
Catalog No.: PC-20629Not For Human Use, Lab Use Only.
SF-1-066 is an orally bioavailable inhibitor of STAT3 with IC50 of 35 uM for inhibition of STAT3 DNA binding activity in vitro, binds to the STAT3 SH2 domain and inhibits STAT3 dimerization.
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SF-1-066 is an orally bioavailable inhibitor of STAT3 with IC50 of 35 uM for inhibition of STAT3 DNA binding activity in vitro, binds to the STAT3 SH2 domain and inhibits STAT3 dimerization.
| M.Wt | 550.67 | |
| Formula | C30H34N2O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Page B. D.,et al. Bioorg. Med. Chem. Lett. 21, 5605–5609
2. Diana Resetca, et al. J Biol Chem. 2014 Nov 21;289(47):32538-47.
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