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Chemical Structure : SGC-CK2-2
Catalog No.: PC-22407Not For Human Use, Lab Use Only.
SGC-CK2-2 is a potent, selective casein kinase 2 (CSNK2, CK2) chemical probe inhibitor with IC50 of 0.2 uM, shows much improved kinase selectivity compared with silmitasertib (CX-4945).
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SGC-CK2-2 is a potent, selective casein kinase 2 (CSNK2, CK2) chemical probe inhibitor with IC50 of 0.2 uM, shows much improved kinase selectivity compared with silmitasertib (CX-4945).
SGC-CK2-2 shows high selectivity (3/403 kinases) in DiscoverX KINOMEscan showing 90% inhibition at 1 µM.
SGC-CK2-2 demonstrated inhibition of viral replication with IC50 of 10-20 uM in MHV-NLuc in DBT cells.
| M.Wt | 330.35 | |
| Formula | C19H14N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Asressu KH, et al. Pharmaceuticals (Basel). 2024 Feb 27;17(3):306.
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