Catalog No.: PC-38622Not For Human Use, Lab Use Only.
SHA68 is a selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50 of 22.0 and 23.8 nM for human NPSR Asn107 and Ile107 variants respectively, Ke value of 13.7 nM (Ile107 variant).
SHA68 is a selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50 of 22.0 and 23.8 nM for human NPSR Asn107 and Ile107 variants respectively, Ke value of 13.7 nM (Ile107 variant).
SHA68 induced antidepressant-like effects in bed nucleus of the stria terminalis (BNST) of learned helplessness (LH) rats (an animal model of depression).
