SI-109 | STAT3 inhibitor | Probechem Biochemicals

Chemical Structure : SI-109

CAS No.: 2429877-30-3

SI-109 (SI 109)

Catalog No.: PC-73110Not For Human Use, Lab Use Only.

SI-109 (SI 109) is a selective, high-affinity and cell-permeable STAT3 SH2 domain inhibitor with Ki of 9 nM, component of STAT3 degrader SD-36 (PROTAC).

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Biological Activity

SI-109 (SI 109) is a selective, high-affinity and cell-permeable STAT3 SH2 domain inhibitor with Ki of 9 nM, component of STAT3 degrader SD-36 (PROTAC).

Physicochemical Properties

M.Wt	808.82
Formula	C40H47F2N6O8P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Month
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((2-(((3S,6S,10aS)-3-(((S)-5-amino-1-(benzhydrylamino)-1,5-dioxopentan-2-yl)carbamoyl)-5-oxodecahydropyrrolo[1,2-a]azocin-6-yl)carbamoyl)-1H-indol-5-yl)difluoromethyl)phosphonic acid

References

1. Bai L, et al. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.

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SI-109 (SI 109)

Biological Activity

Physicochemical Properties

References

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