Catalog No.: PC-70209Not For Human Use, Lab Use Only.
SI-113 (SI 113) is a potent, specific inhibitor of the SGK1 kinase activity with IC50 of 600 nM, induces autophagy, apoptosis and ER stress in cancer cells.
SI-113 (SI 113) is a potent, specific inhibitor of the SGK1 kinase activity with IC50 of 600 nM, induces autophagy, apoptosis and ER stress in cancer cells.
SI-113 blocks insulin-dependent phosphorylation of the Sgk1 substrate Mdm2, and induces necrosis and apoptosis in RKO cells.
SI-113 potentiates the effects of paclitaxel on cell viability; active in vivo.
