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Chemical Structure : SIG-1191
Catalog No.: PC-35772Not For Human Use, Lab Use Only.
SIG-1191 (SIG1191) is a soprenylcysteine (IPC) small molecule with anti-inflammatory activity, inhibits UVB-induced inflammation blocking pro-inflammatory cytokine interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) production.
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SIG-1191 (SIG1191) is a soprenylcysteine (IPC) small molecule with anti-inflammatory activity, inhibits UVB-induced inflammation blocking pro-inflammatory cytokine interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) production.
SIG-1191 increases AQP3 expression in cultured normal human epidermal keratinocytes, dose dependently increased AQP3 protein levels.
| M.Wt | 495.679 | |
| Formula | C25H41N3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Fernández JR, et al. Arch Dermatol Res. 2017 Mar;309(2):103-110.
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