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Chemical Structure : SJPYT-306
Catalog No.: PC-22400Not For Human Use, Lab Use Only.
SJPYT-306 is a potent, selective dual antagonist and inverse agonist of pregnane X receptor (PXR) with binding IC50 of 6 nM, inverse agonist and antagonist IC50 of 1 nM and 14 nM, respectively.
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SJPYT-306 is a potent, selective dual antagonist and inverse agonist of pregnane X receptor (PXR) with binding IC50 of 6 nM, inverse agonist and antagonist IC50 of 1 nM and 14 nM, respectively.
| M.Wt | 480.61 | |
| Formula | C27H36N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yongtao Li, et al. J Med Chem. 2022 Dec 22;65(24):16829-16859.
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