Chemical Structure : SJPYT-318
Catalog No.: PC-21198Not For Human Use, Lab Use Only.
SJPYT-318 is a highly selective pregnane X receptor (PXR) agonist, targets PXR ligand-binding domain (LBD), exhibits selectivity for PXR LBD over LXR LBDs for recruiting SRC-1.
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SJPYT-318 is a highly selective pregnane X receptor (PXR) agonist, targets PXR ligand-binding domain (LBD), exhibits selectivity for PXR LBD over LXR LBDs for recruiting SRC-1.
SJPYT-318 is strongly selective for PXR in cellular reporter activation, showing only marginal activation of both LXRα and LXRβ.
M.Wt | 581.53 | |
Formula | C28H21F6NO4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Huber AD, et al. Structure. 2023 Sep 5:S0969-2126(23)00297-6.
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