SJPYT-328 | PXR agonist | Probechem Biochemicals

Chemical Structure : SJPYT-328

Catalog No.: PC-22402Not For Human Use, Lab Use Only.

SJPYT-328 is a potent, selective pregnane X receptor (PXR) agonist with binding IC50 of 48 nM, agonism IC50 of 7.1 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SJPYT-328 is a potent, selective pregnane X receptor (PXR) agonist with binding IC50 of 48 nM, agonism IC50 of 7.1 nM.

M.Wt	508.66
Formula	C29H40N4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(5-(tert-butyl)-2-(hexan-3-yloxy)phenyl)-1-(2,4-dimethoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide

1. Garcia-Maldonado E, et al. Nat Commun. 2024 May 14;15(1):4054.