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Chemical Structure : SJPYT-331
Catalog No.: PC-22401Not For Human Use, Lab Use Only.
SJPYT-331 is a potent, selective pregnane X receptor (PXR) antagonist with binding IC50 of 3.6 nM, antagonistic IC50 of 7.1 nM.
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SJPYT-331 is a potent, selective pregnane X receptor (PXR) antagonist with binding IC50 of 3.6 nM, antagonistic IC50 of 7.1 nM.
SJPYT-331 blocks agonist-induced PXR activation in primary human hepatocytes (PHH).
| M.Wt | 496.56 | |
| Formula | C26H32N4O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Garcia-Maldonado E, et al. Nat Commun. 2024 May 14;15(1):4054.
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