Chemical Structure : SKF83959 hydrobromide
CAS No.: 67287-95-0
Catalog No.: PC-25927Not For Human Use, Lab Use Only.
SKF83959 hydrobromide is a potent and selective dopamine D1-like receptor partial agonist with binding Ki of 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively, also is a potent allosteric modulator of Sigma 1 receptor (S1R), shows anti-seizure activities.
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|---|---|---|---|
| 5 mg | $218 | In stock | |
| 10 mg | $358 | In stock | |
| 25 mg | $558 | In stock | |
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SKF83959 hydrobromide is a potent and selective dopamine D1-like receptor partial agonist with binding Ki of 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively, also is a potent allosteric modulator of Sigma 1 receptor (S1R), shows anti-seizure activities.
| M.Wt | 398.73 | |
| Formula | C18H21BrClNO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6-chloro-3-methyl-1-(m-tolyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide |
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1. Panchalingam S, et al. Neuropharmacology. 2001 May;40(6):826-37.
2. Jin LQ, et al. J Neurochem. 2003 Apr;85(2):378-86.

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