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Chemical Structure : SKLB-197
CAS No.: 2713577-16-1
Catalog No.: PC-72744Not For Human Use, Lab Use Only.
SKLB-197 is a potent and highly selective ATR kinase inhibitor with IC50 of 13 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 25 mg | $558 | In stock | |
| 100 mg | $1480 | In stock | |
| 1 g | Get quote |
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SKLB-197 is a potent and highly selective ATR kinase inhibitor with IC50 of 13 nM.
SKLB-197 displays very weak or no activity against other a panel of 402 protein kinases.
SKLB-197 exhibited potent antitumor activity against ATM-deficent tumors both in vitro and in vivo, with good pharmacokinetic properties.
| M.Wt | 424.508 | |
| Formula | C25H24N6O | |
| Appearance | Solid | |
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1. Huachao Bin, et al. Eur J Med Chem. 2022 Mar 15;232:114187.
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