Catalog No.: PC-23460Not For Human Use, Lab Use Only.
SKLB1028 (Ruserontinib) is a potent, oral multikinase inhibitor of EGFR, FLT3 and Abl with IC50 of 55 nM (FLT3), potently inhibits the wild-type and L858R-mutant EGFR with IC50 values of 31 nM and 4 nM, respectively.
SKLB1028 (Ruserontinib) is a potent, oral multikinase inhibitor of EGFR, FLT3 and Abl with IC50 of 55 nM (FLT3), potently inhibits the wild-type and L858R-mutant EGFR with IC50 values of 31 nM and 4 nM, respectively. SKLB1028 (Ruserontinib) displays exceptional activity in FLT3‐driven AML. SKLB1028 has strong anti‐leukemia effects both in vivo and in vitro.
