Catalog No.: PC-23014Not For Human Use, Lab Use Only.
SLC13A3 inhibitor ACA ((E/Z)-BML264) is a small molecule inhibitor of SLC13A3, also is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker.
SLC13A3 inhibitor ACA ((E/Z)-BML264) is a small molecule inhibitor of SLC13A3, also is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. SLC13A3 inhibitor ACA suppresses the growth of human HCC cells and prevents β-catenin-driven hepatocarcinogenesis in vivo. SLC13A3 inhibitor ACA is also an effective reversible inhibitor of calcium-activated chloride channels, has potential to treat arrhythmia.
Physicochemical Properties
M.Wt
337.42
Formula
C21H23NO3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-(p-amylcinnamoyl) anthranilic acid
References
1. Wennan Zhao, et al. Nat Commun. 2024 Aug 30;15(1):7522.
2. Bunse, L. et al. Nat. Med24, 1192–1203 (2018).
3. Kraft R, et al. Br J Pharmacol. 2006 Jun;148(3):264-73.
