SM-7368 | NF-κB inhibitor | Probechem Biochemicals

Chemical Structure : SM-7368

CAS No.: 380623-76-7

SM-7368 (SM7368)

Catalog No.: PC-24658Not For Human Use, Lab Use Only.

SM-7368 is a small molecule NF-kB inhibitor, inhibits TNF-alpha-induced MMP-9 upregulation, strongly inhibits TNF-alpha-induced NF-kappaB activity but not AP-1 activity.

Packing	Price	Stock
10 mg	$78	In stock
25 mg	$118	In stock
50 mg	$188	In stock
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

SM-7368 is a small molecule NF-kB inhibitor, inhibits TNF-alpha-induced MMP-9 upregulation, strongly inhibits TNF-alpha-induced NF-kappaB activity but not AP-1 activity.
SM-7368 strongly inhibits the TNF-alpha-induced invasion of HT1080 human fibrosarcoma cell line.

Physicochemical Properties

M.Wt	328.68
Formula	C10H5ClN4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Chloro-4-nitro-N-(5-nitrothiazol-2-yl)benzamide

References

1. Lee HY, et al. Biochem Biophys Res Commun. 2005 Oct 21;336(2):716-22.

2. Samuel T, et al. BMC Cancer. 2014 Aug 18;14:599.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

SM-7368 (SM7368)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.