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Chemical Structure : SMCC-DM1
CAS No.: 1228105-51-8
Catalog No.: PC-42307Not For Human Use, Lab Use Only.
A thioether linker conjugated with potent microtubule-disrupting agent DM1 (mertansine)..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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A thioether linker conjugated with potent microtubule-disrupting agent DM1 (mertansine).
| M.Wt | 1072.61164 | |
| Formula | C51H66ClN5O16S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Maytansine, N2'-deacetyl-N2'-[3-[[1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]- |
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1. Erickson HK, et al. Cancer Res. 2006 Apr 15;66(8):4426-33.
2. Ikeda H, et al. Clin Cancer Res. 2009 Jun 15;15(12):4028-37.
3. Erickson HK, et al. Bioconjug Chem. 2010 Jan;21(1):84-92.
4. Kellogg BA, et al. Bioconjug Chem. 2011 Apr 20;22(4):717-27.
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