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SMEPPI

Chemical Structure : SMEPPI

CAS No.: 1274881-60-5

SMEPPI

Catalog No.: PC-23849Not For Human Use, Lab Use Only.

SMEPPI is a small molecule inhibitor of expression and activation of NF-κB p65, induces NF-κB p65 proteasomal degradation and has anti-diabetic and anti-inflammatory activities.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SMEPPI is a small molecule inhibitor of expression and activation of NF-κB p65, induces NF-κB p65 proteasomal degradation and has anti-diabetic and anti-inflammatory activities.

Physicochemical Properties

M.Wt 526.55
Formula C27H24F2N2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(2-(1,1-dioxidothiomorpholino) ethoxy)-3-(2,4-difluorophenyl)-2-(6-methoxypyridin-3-yl)-1H-inden-1-one

References

1. Ji Hyun Oh, et al. Biomed Pharmacother. 2025 Jan 14:183:117856.

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