SN-013 | STING inhibitor | Probechem Biochemicals

Chemical Structure : SN-013

SN-013 (SN013)

Catalog No.: PC-22730Not For Human Use, Lab Use Only.

SN-013 is a potent, selective STING inhibitor, inhibits 2′3′-cGAMP-induced Ifnb gene expression with IC50 of 101.5 nM and 539.6 nM in MEF and HFF cells, respectively, targets the cyclic dinucleotide binding pocket.

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Biological Activity

Physicochemical Properties

M.Wt	382.43
Formula	C20H18N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-hydroxy-3-(methylsulfonamido)phenyl)-[1,1'-biphenyl]-4-carboxamide

References

1. Hong Z, et al. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2105465118.

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SN-013 (SN013)

Biological Activity

Physicochemical Properties

References

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