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Chemical Structure : SNAP-7941
Catalog No.: PC-61528Not For Human Use, Lab Use Only.
SNAP-7941 is a selective, high-affinity, and competitive MCH1 receptor (MCHR1) antagonist with Ki of 15 nM.
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SNAP-7941 is a selective, high-affinity, and competitive MCH1 receptor (MCHR1) antagonist with Ki of 15 nM.
SNAP-7941 inhibits food intake stimulated by central administration of MCH, reduces consumption of palatable food, decreases in body weight in rats with diet-induced obesity.
SNAP-7941 also produces effects similar to clinically used antidepressants and anxiolytics in animal models of depression/anxiety.
| M.Wt | 641.704 | |
| Formula | C33H41F2N5O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Borowsky B, et al. Nat Med. 2002 Aug;8(8):825-30.
2. Basso AM, et al. Eur J Pharmacol. 2006 Jul 1;540(1-3):115-20.
3. Millan MJ, et al. Int J Neuropsychopharmacol. 2008 Dec;11(8):1105-22.
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