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Chemical Structure : SNAP-94847
Catalog No.: PC-61527Not For Human Use, Lab Use Only.
SNAP-94847 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 1.69 nM.
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SNAP-94847 is a selective, high-affinity, and competitive MCH1 receptor (MCH1-R) antagonist with Ki of 1.69 nM; displays an anxiolytic/antidepressant-like effect in mouse models, stimulates the proliferation of progenitors in the dentate gyrus; has a unique anxiolytic-like profile that is distinct from selective serotonin reuptake inhibitors and tricyclic antidepressants.
Obesity
Discontinued
| M.Wt | 478.572 | |
| Formula | C29H32F2N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. David DJ, et al. J Pharmacol Exp Ther. 2007 Apr;321(1):237-48.
2. Chen CA, et al. J Med Chem. 2007 Aug 9;50(16):3883-90.
3. Nair SG, et al. Psychopharmacology (Berl). 2009 Jul;205(1):129-40.
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