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Chemical Structure : SNAP 37889
CAS No.: 303149-14-6
Catalog No.: PC-42234Not For Human Use, Lab Use Only.
SNAP 37889 (HT-2157) is a potent, selective galanin-3 receptor (GalR3) antagonist with Ki of 17.44 nM, displays highly selective for Gal3 over the Gal1 and Gal2 subtypes (both Ki >10 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $378 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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SNAP 37889 (HT-2157) is a potent, selective galanin-3 receptor (GalR3) antagonist with Ki of 17.44 nM, displays highly selective for Gal3 over the Gal1 and Gal2 subtypes (both Ki >10 uM).
SNAP 37889 (HT-2157) attenuates stress-induced hyperthermia in mice, partially antagonizes the galanin-evoked reduction in hippocampal serotonin, exhibits anxiolytic- and antidepressant-like profiles in vivo.
| M.Wt | 366.3359 | |
| Formula | C21H13F3N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 29 mg/mL |
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| Chemical Name/SMILES |
2H-Indol-2-one, 1,3-dihydro-1-phenyl-3-[[3-(trifluoromethyl)phenyl]imino]- |
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1. Swanson CJ, et al. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94.
2. Ash BL, et al. Regul Pept. 2011 Jan 17;166(1-3):59-67.
3. Koller A, et al. Neuropeptides. 2016 Apr;56:83-8.
4. Scheller KJ, et al. Neuropharmacology. 2017 May 15;118:1-12.
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