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Chemical Structure : SNC80
CAS No.: 156727-74-1
Catalog No.: PC-70349Not For Human Use, Lab Use Only.
SNC80 (NIH-10815) is a highly selective, non-peptide agonist of the δ-opioid receptor (δ-OR) with IC50/Ki of 2.73/0.18 nM.
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|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $428 | In stock | |
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SNC80 (NIH-10815) is a highly selective, non-peptide agonist of the δ-opioid receptor (δ-OR) with IC50/Ki of 2.73/0.18 nM.
SNC80 displays >2,000-fold selectivity over the μ-opioid receptor.
SNC80 selectively activates μ-δ heteromers to produce maximal antinociception.
| M.Wt | 449.6 | |
| Formula | C28H39N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-[(R)-[(2S,5R)-2,5-dimethyl-4-(2-propen-1-yl)-1-piperazinyl](3-methoxyphenyl)methyl]-N,N-diethyl-benzamide |
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1. Calderon SN, et al. J Med Chem. 1994 Jul 8;37(14):2125-8.
2. Bilsky EJ, et al. J Pharmacol Exp Ther. 1995 Apr;273(1):359-66.
3. Metcalf MD, et al. ACS Chem Neurosci. 2012 Jul 18;3(7):505-9.
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