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SOM3355

Chemical Structure : SOM3355

CAS No.: 42864-78-8

SOM3355 (Bevantolol hydrochloride)

Catalog No.: PC-26994Not For Human Use, Lab Use Only.

Bevantolol hydrochloride (SOM3355) is a CNS-permeant, selective β1-adrenergic receptor antagonist with pKi value of 7.83 in rat cerebral cortex, also shows additional VMAT2 and VMAT1 inhibition activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Bevantolol hydrochloride (SOM3355) is a CNS-permeant, selective β1-adrenergic receptor antagonist with pKi value of 7.83 in rat cerebral cortex, also shows additional VMAT2 and VMAT1 inhibition activity.

Physicochemical Properties

M.Wt 381.90
Formula C20H28ClNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-((3,4-Dimethoxyphenethyl)amino)-3-(m-tolyloxy)propan-2-ol hydrochloride

References

1. Gamez J, et al. Br J Clin Pharmacol. 2023 May;89(5):1656-1664.

2. Turilli-Ghisolfi ES, et al. Front Pharmacol. 2026 May 19;17:1824708.

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