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SP-100030

Chemical Structure : SP-100030

CAS No.: 154563-54-9

SP-100030 (SP100030)

Catalog No.: PC-22244Not For Human Use, Lab Use Only.

SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor with IC50 of 50 nM for both, inhibits T cell activation.

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5 mg $128 In stock
10 mg $198 In stock
25 mg $348 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor with IC50 of 50 nM for both, inhibits T cell activation.

Physicochemical Properties

M.Wt 437.65
Formula C14H5ClF9N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3,5-Bis(trifluoromethyl)phenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide

References

1. Sullivan RW, et al. J Med Chem. 1998;41(4):413-419.

2. Gerlag DM, et al. J Immunol. 2000;165(3):1652-1658.

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