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Chemical Structure : SP4206
Catalog No.: PC-62479Not For Human Use, Lab Use Only.
SP4206 is a high-affinity (Kd=70 nM) small molecule that blocks the binding of the IL-2α receptor (IL-2Rα) to IL-2.
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SP4206 is a high-affinity (Kd=70 nM) small molecule that blocks the binding of the IL-2α receptor (IL-2Rα) to IL-2.
SP4206 targets virtually the same critical "hot-spot" residues on IL-2 that drive binding of IL-2Rα.
| M.Wt | 662.57 | |
| Formula | C30H37Cl2N7O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14.
2. Thanos CD, et al. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15422-7.
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