SPDB |CAS:115088-06-7 Probechem Biochemicals

Chemical Structure : SPDB

CAS No.: 115088-06-7

Catalog No.: PC-43038Not For Human Use, Lab Use Only.

SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs)..

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25 mg	$145	In stock
50 mg	$215	In stock
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Biological Activity

SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).

M.Wt	326.3913
Formula	C13H14N2O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Butanoic acid, 4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester

1. Cumber AJ, et al. Bioconjug Chem. 1992 Sep-Oct;3(5):397-401.

2. Erickson HK, et al. Cancer Res. 2006 Apr 15;66(8):4426-33.

3. Ikeda H, et al. Clin Cancer Res. 2009 Jun 15;15(12):4028-37.

4. Zhao RY, et al. J Med Chem. 2011 May 26;54(10):3606-23.