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SPI009

Chemical Structure : SPI009

CAS No.: 1008671-41-7

SPI009 (SPI 009)

Catalog No.: PC-61788Not For Human Use, Lab Use Only.

SPI009 is a novel antipersister compound active against P. aeruginosa.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SPI009 is a novel antipersister compound active against P. aeruginosa, reduces the number of persisters up to 100,000-fold in both lab strains and clinical isolates of P. aeruginosa when combined with distinct classes of antibiotics.
    SPI009 efficiently kills persister cells with minor cytotoxicity, and causes no erythrocyte damage.

    Physicochemical Properties

    M.Wt 340.244
    Formula C17H19Cl2NO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-[(2,4-dichlorophenethyl)amino]-3-phenoxypropan-2-ol

    References

    1. Liebens V, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00836-17.

    2. Defraine V, et al. Front Microbiol. 2017 Dec 22;8:2585.

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