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SPR719

Chemical Structure : SPR719

CAS No.: 1384984-18-2

SPR719 (SPR 719)

Catalog No.: PC-72064Not For Human Use, Lab Use Only.

SPR719 (SPR 719) is a novel mycobacterial DNA gyrase inhibitor with bactericidal properties, inhibits M. abscessu with MIC 0.6 uM (abscessus ATCC 19977).

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Biological Activity

SPR719 (SPR 719) is a novel mycobacterial DNA gyrase inhibitor with bactericidal properties, inhibits M. abscessu with MIC 0.6 uM (abscessus ATCC 19977).

Physicochemical Properties

M.Wt 428.468
Formula C21H25FN6O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-ethyl-3-(6-fluoro-5-(2-(2-hydroxypropan-2-yl)pyrimidin-5-yl)-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-2-yl)urea

References

1. Negatu DA, et al. Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0067621.

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