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SPR741 acetate

Chemical Structure : SPR741 acetate

CAS No.: 2994332-02-2

SPR741 acetate (NAB741 acetate)

Catalog No.: PC-23144Not For Human Use, Lab Use Only.

SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and antibiotic adjuvant, increases the permeability of the outer membrane of Gram-negative bacteria.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and antibiotic adjuvant, increases the permeability of the outer membrane of Gram-negative bacteria.

Physicochemical Properties

M.Wt 1052.20
Formula C46H77N13O15
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

C(C)(O)=O.C([C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCN)C(=O)N[C@@H](CCN)C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC[C@H](NC([C@H](NC([C@@H](NC(C)=O)[C@@H](C)O)=O)CO)=O)C(=O)N[C@@H](CCN)C(=O)N1)[H])C2=CC=CC=C2

References

1. Mendes RE, et al. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e00742-20.

2. Stainton SM, et al. Antimicrob Agents Chemother. 2018 Jun 26;62(7):e00239-18.

3. Corbett D, et al. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00200-17.

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