Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : SPX-101
Catalog No.: PC-63534Not For Human Use, Lab Use Only.
SPX-101 is a specific, peptide mimetic promoter of epithelial sodium channel (ENaC) internalization, binds selectively to ENaC and promotes internalization of the α-, β-, and γ-subunits.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SPX-101 is a specific, peptide mimetic promoter of epithelial sodium channel (ENaC) internalization, binds selectively to ENaC and promotes internalization of the α-, β-, and γ-subunits.
SPX-101 promotes durable reduction of ENaC membrane concentration, increases mucus transport in the β-ENaC mouse model as well as the sheep model of CF.
| M.Wt | 1179.385 | |
| Formula | C53H90N14O16 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Scott DW, et al. Am J Respir Crit Care Med. 2017 Sep 15;196(6):734-744.
2. Lennox A, et al. Am J Respir Crit Care Med. 2017 Sep 15;196(6):671-672.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
