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Chemical Structure : SR-16835
Catalog No.: PC-61540Not For Human Use, Lab Use Only.
SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM).
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SR-16835 is a potent full agonist of ORL1 receptor (NOP receptor) with binding Ki of 11.4 nM, with low-affinity mu-opioid partial agonist activity (Ki=79.9 nM).
SR-16835 does not produce conditioned place preference (CPP) alone, but attenuates morphine CPP.
SR-16835 shows antiallodynic activity in mice model of chronic pain.
| M.Wt | 386.54 | |
| Formula | C26H30N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Toll L, et al. J Pharmacol Exp Ther. 2009 Dec;331(3):946-53.
2. Khroyan TV, et al. J Pharmacol Exp Ther. 2011 Nov;339(2):687-93.
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