Catalog No.: PC-62696Not For Human Use, Lab Use Only.
SR-18292 (SR18292) is a potent PGC-1α inhibitor, increases PGC-1α acetylation, suppresses gluconeogenic gene expression, and reduce glucose production in hepatocytes.
SR-18292 (SR18292) is a potent PGC-1α inhibitor, increases PGC-1α acetylation, suppresses gluconeogenic gene expression, and reduce glucose production in hepatocytes.
SR-18292 increases the interaction of PGC-1α with GCN5 and reduces transcriptional activity of HNF4α.
SR-18292 reduces fasting blood glucose, increases hepatic insulin sensitivity, and improves glucose homeostasis in diabetic mice.
