Chemical Structure : SR-4370
CAS No.: 1816294-67-3
Catalog No.: PC-24027Not For Human Use, Lab Use Only.
SR-4370 is a novel HDAC inhibitor with IC50 of 0.13/0.5/0.006/3.4/2.3 μM for HDAC1/2/3/6/8, respectively, also is a latency-reversing agent (LRA) for reactivation of latent HIV-1.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $88 | In stock | |
10 mg | $128 | In stock | |
25 mg | $218 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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SR-4370 is a novel HDAC inhibitor with IC50 of 0.13/0.5/0.006/3.4/2.3 μM for HDAC1/2/3/6/8, respectively, also is a latency-reversing agent (LRA) for reactivation of latent HIV-1.
SR-4370 also ameliorated dmd mutant zebrafish skeletal muscle degeneration.
M.Wt | 304.34 | |
Formula | C17H18F2N2O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2',3'-difluoro-[1,1'-biphenyl]-4-carboxylic acid, 2-butylhydrazide |
1. Zutz A, et al. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01815-20.
2. Patent WO 2015153516 A1.
3. Louie KW, et al. bioRxiv [Preprint]. 2025 Jan 27:2025.01.24.634796.
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