Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-HDAC-SR-4370
SR-4370

Chemical Structure : SR-4370

CAS No.: 1816294-67-3

SR-4370 (SR4370)

Catalog No.: PC-24027Not For Human Use, Lab Use Only.

SR-4370 is a novel HDAC inhibitor with IC50 of 0.13/0.5/0.006/3.4/2.3 μM for HDAC1/2/3/6/8, respectively, also is a latency-reversing agent (LRA) for reactivation of latent HIV-1.

Packing Price Stock Quantity
5 mg $88 In stock
10 mg $128 In stock
25 mg $218 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SR-4370 is a novel HDAC inhibitor with IC50 of 0.13/0.5/0.006/3.4/2.3 μM for HDAC1/2/3/6/8, respectively, also is a latency-reversing agent (LRA) for reactivation of latent HIV-1.
SR-4370 also ameliorated dmd mutant zebrafish skeletal muscle degeneration.

Physicochemical Properties

M.Wt 304.34
Formula C17H18F2N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2',3'-difluoro-[1,1'-biphenyl]-4-carboxylic acid, 2-butylhydrazide

References

1. Zutz A, et al. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01815-20.

2. Patent WO 2015153516 A1.

3. Louie KW, et al. bioRxiv [Preprint]. 2025 Jan 27:2025.01.24.634796.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: