SR-THAP

Chemical Structure : SR-THAP

Catalog No.: PC-25993Not For Human Use, Lab Use Only.

SR-THAP is a selective inhibitor of human GABA transporter GAT3 with IC50 of 4.9 uM, shows no inhibition on GAT1.

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Biological Activity

SR-THAP is a selective inhibitor of human GABA transporter GAT3 with IC50 of 4.9 uM, shows no inhibition on GAT1.

M.Wt	517.62
Formula	C31H35NO6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Pyrrolidineacetic acid, α-hydroxy-1-[(2E)-4,4,4-tris(4-methoxyphenyl)-2-buten-1-yl]-, (αS,2R)-

1. Mortensen JS, et al. Nat Commun. 2026 Jan 29. doi: 10.1038/s41467-026-68479-0.